Peter Margetts received both MD and PhD from McMaster University and was subsequently recruited on faculty as a clinician scientist. His clinical practice involves general nephrology, chronic kidney disease, and dialysis with a special interest in peritoneal dialysis. His educational contributions for the University includes teaching at the undergraduate and post graduate medical school and he is presently the director of the recently developed MD/PhD programme at McMaster University.
He is a member of the Hamilton Centre for Kidney Research and the Centre for Gene Therapeutics and runs a basic research laboratory with interests in peritoneal dialysis, progressive renal disease and gene therapy. Specific projects include assessment of the effects of transforming growth factor β on the peritoneal membrane, an examination of the mechanisms of epithelial mesenchymal transition including hypoxia and various growth factors, and the interaction between fibrosis and angiogenesis. The lab is also very interested in optimizing gene therapy techniques and using modified first and third generation adenovirus to facilitate gene transfer to the peritoneum and kidney.
Dr. Margetts also collaborates with colleagues in human clinical and translational studies including evaluation of novel methods of volume assessment and the interaction between markers of inflammation, volume expansion, cardiovascular disease, and clinical outcomes.
MARGETTS, PETER J. MD PhD FRCPC
Associate Professor, Department of Medicine, McMaster University
Staff Nephrologist, Division of Nephrology, St. Joseph’s Hospital
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